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Assisted Reproductive Technologies and Infectious Diseases: by Andrea Borini, Maria Valeria Savasi PDF

By Andrea Borini, Maria Valeria Savasi

ISBN-10: 3319301101

ISBN-13: 9783319301105

ISBN-10: 3319301128

ISBN-13: 9783319301129

This concise and sensible ebook is the 1st of its variety to check using assisted reproductive applied sciences (ART) in terms of blood-borne infectious ailments: human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV). The ebook opens with a dialogue of the impression of those viruses on female and male fertility, by way of particular chapters of every of them, together with artwork with HIV and HCV serodiscordant (where both the male or girl is confident) and the detection and impression of HBV and HCV in human gametes and embryos. a huge personality on laboratory security while acting paintings with blood-borne viruses follows, and the booklet concludes with a dialogue of paintings in austere and resource-poor settings, the place those infections are usually dominant because of loss of remedy and entry to vaccines. Written and edited by way of a world array of specialists in reproductive medication, Assisted Reproductive applied sciences and Infectious ailments explores questions, concepts, and similar concerns with the purpose of successfully supporting clinicians operating with serodiscordant wishing to have young ones.

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Extra resources for Assisted Reproductive Technologies and Infectious Diseases: A Guide to Management

Example text

51. Else LJ, et al. Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract. Antivir Ther. 2011;16(8):1149–67. 52. Vernazza PL, et al. Preexposure prophylaxis and timed intercourse for HIV-discordant couples willing to conceive a child. AIDS. 2011;25(16):2005–8. 26 E. van Leeuwen 53. Whetham J, et al. Pre-exposure prophylaxis for conception (PrEP-C) as a risk reduction strategy in HIV-positive men and HIV-negative women in the UK. AIDS Care. 2014;26(3):332–6.

For this reason, several genotypes such as D, E, G and 50 G. Zehender et al. some B and C subgenotypes are more frequently subjected to preC/C mutation. In contrast, BCP mutations are more prominent in HBV genotypes A, F and the other HBV B and C subgenotypes. These data suggest that subjects infected by some HBV genotypes (D, E, G) are more likely to be affected by HBeAg-negative chronic hepatitis [120]. In general, Asian subjects have a longer persistence of HBeAg positivity in their blood. The anti-HBe seroconversion occurs earlier and more frequently in subjects infected with genotype B than in those with genotype C [121].

57. Were EO, et al. Pre-exposure prophylaxis does not affect the fertility of HIV-1-uninfected men. AIDS. 2014;28(13):1977–82. 58. Gregson S, Zaba B, Garnett GP. Low fertility in women with HIV and the impact of the epidemic on orphanhood and early childhood mortality in sub-Saharan Africa. AIDS. 1999;13(Suppl A):S249–57. 59. Lo JC, Schambelan M. Reproductive function in human immunodeficiency virus infection. J Clin Endocrinol Metab. 2001;86(6): 2338–43. 60. Linas BS, et al. Relative time to pregnancy among HIV-infected and uninfected women in the Women’s Interagency HIV Study, 20022009.

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Assisted Reproductive Technologies and Infectious Diseases: A Guide to Management by Andrea Borini, Maria Valeria Savasi

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